New Insights on Exercise Intensity and Mortality: Is More Vigorous Activity Better?

Looking to maximize your health benefits? This large study suggests adding bursts of vigorous activity to your routine, even if you already meet moderate-intensity exercise recommendations, could significantly lower your risk of death from any cause.

DR ANITA JAMWAL MS

9/1/20246 min read

https://www.frontiersin.org/files/Articles/495741/fpsyg-10-02790-HTML/image_m/fpsyg-10-02790-g001.jp
https://www.frontiersin.org/files/Articles/495741/fpsyg-10-02790-HTML/image_m/fpsyg-10-02790-g001.jp

The study published in the journal JAMA Internal Medicine found that moderate-to-vigorous physical activity was associated with a lower risk of all-cause mortality compared to low-to-no physical activity. Specifically, there was a 37% lower risk of all-cause mortality for those who engaged in moderate-to-vigorous physical activity compared to those who engaged in low-to-no physical activity. The study also found that there was a 41% lower risk of death from ischemic heart disease for those who engaged in moderate-to-vigorous physical activity compared to those who engaged in low-to-no physical activity. Additionally, there was a 27% lower risk of death from cancer for those who engaged in moderate-to-vigorous physical activity compared to those who engaged in low-to-no physical activity.

Key Points

Ever wonder if pushing yourself a little harder during your workout could pay off? A recent study suggests it might! Researchers followed over 400,000 adults and found that those who incorporated more vigorous activities like running or HIIT into their exercise routine, even if they already met recommended guidelines, had a significantly lower risk of death from any cause.

Here's the breakdown:

  • The study analyzed self-reported physical activity data from over 400,000 adults over 10 years.

  • The finding: Participants who included more vigorous exercise in their routine, regardless of total exercise time, had a 17% lower risk of death compared to those with no vigorous activity.

  • The surprise: This benefit wasn't linked to specific causes like heart disease or cancer death, but rather overall mortality.

While the study can't definitively prove cause and effect, it suggests:

  • The intensity of your workout matters. Brisk walking is great, but incorporating some sprints or jumping jacks could offer additional health benefits.

  • Every bit counts. Even small increases in vigorous activity might be impactful.

  • More research is needed. We need to understand the mechanisms behind this link and whether vigorous activity also protects against specific diseases.

The bottom line: Consider adding some high-intensity bursts to your exercise routine. While moderate activity is crucial, this study suggests that upping the tempo could be a valuable investment in your long-term health.


The Link Between Vigorous Physical Activity and Mortality: Unraveling the Importance

In pursuit of longevity and well-being, understanding the nuances of physical activity becomes paramount. Emerging from the depths of data lies a pivotal question: does the ratio of vigorous physical activity (VPA) to total physical activity hold the key to mortality reduction? Let's embark on an investigative journey to dissect the significance of this relationship and its implications for health.

Deciphering the Significance

In the labyrinth of health recommendations, the spotlight often shines on moderate-to-vigorous-intensity physical activity (MVPA). It's a well-trodden path guided by the premise that a certain volume of physical exertion promises health dividends. But what about the quality of this activity? Does the intensity matter more than the duration?

  • Unveiling the Hypothesis: The hypothesis is straightforward yet profound: a higher proportion of VPA, when compared to total MVPA, is expected to correlate with a lower mortality risk. But does reality mirror this expectation?

Methods:

  • Analyzed data from 403,681 adults within the National Health Interview Survey (NHIS) 1997–2013.

  • Self-reported physical activity data and linkage to the National Death Index records through December 31, 2015, were utilized.

  • The median follow-up duration was 10.1 years.

  • Cox proportional hazard regression models were employed to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) adjusted for sociodemographic factors, lifestyle risk factors, and total MVPA.

Key Findings:

  • All-cause mortality: A higher proportion of VPA to total MVPA was associated with lower all-cause mortality, independent of total MVPA. Compared to no VPA, participants allocating over 50% to 75% of their exercise time to VPA exhibited a 17% reduced all-cause mortality risk (HR: 0.83; 95% CI: 0.78–0.88).

  • CVD mortality: A similar trend was observed for CVD mortality, with statistically significant associations seen for participants devoting over 50% to 75% or over 75% to 99% of their exercise time to VPA.

  • Cancer mortality: A higher VPA proportion also correlated with lower cancer mortality, though statistically significant associations were limited to the same two VPA categories as with CVD mortality.

  • Subgroup analysis: The associations remained consistent across sociodemographic, lifestyle, and chronic condition subgroups, except for smokers, who exhibited attenuated effects.

  • Sensitivity analysis: Excluding early deaths, using different analytic approaches, and considering competing risks yielded consistent results or potential overestimations of CVD and cancer mortality HRs in the main analysis.

  • Joint effects of MPA and VPA: Exploratory analysis suggested the potential for the lowest all-cause mortality risk with a combined 150–299 minutes/week of moderate-intensity physical activity (MPA) and 150+ minutes/week of VPA.

  • Comparison with MVPA guidelines: While meeting recommended MVPA guidelines offered substantial benefits, the study suggests potential additional advantages from incorporating VPA.

Cl:nical Implications

The study found that people who included a higher proportion of VPA in their overall physical activity, regardless of total exercise time, had a significantly lower risk of death compared to those with no VPA. This benefit was strongest for individuals who devoted over half of their exercise time to vigorous activities. While the link between VPA and death from specific causes like heart disease and cancer was less clear, the study suggests potential advantages for higher VPA proportions in these areas as well. The findings highlight the potential value of adding some bursts of high-intensity exercise to your routine, even if you already engage in moderate-intensity activities like brisk walking. However, it's important to remember that this is an observational study and cannot definitively prove cause-and-effect. Further research is needed to fully understand the mechanisms behind these associations and explore optimal combinations of moderate and vigorous exercise for specific health outcomes.


Conclusion:

This study provides robust evidence that a higher proportion of VPA to total MVPA is associated with significantly lower mortality risk from all causes, including CVD and potentially cancer. These findings support the potential benefits of incorporating vigorous activity into physical activity routines, even for individuals meeting current MVPA recommendations. Further research is warranted to elucidate the underlying mechanisms and explore optimal combinations of moderate- and vigorous-intensity exercise for specific health outcomes.

Faqs

1. What is the association between physical activity and mortality?

Physical activity is strongly associated with reduced mortality risk. Regular physical activity can lower the risk of premature death by reducing the likelihood of developing chronic diseases like heart disease, diabetes, and certain cancers. People who engage in consistent physical activity tend to live longer and have a lower risk of dying from these conditions compared to those who are inactive.

2. What is the intensity of exercise for all-cause mortality?

Moderate to vigorous intensity exercise is most effective in reducing the risk of all-cause mortality. The general guideline is at least 150 minutes of moderate-intensity aerobic activity, such as brisk walking, or 75 minutes of vigorous-intensity activity, like running, per week. Higher intensity and longer duration typically lead to greater reductions in mortality risk, though even light physical activity can contribute to health benefits.

3. What is the association of physical activity history with physical function and mortality in old age?

A history of regular physical activity is associated with better physical function and lower mortality in old age. Individuals who have been physically active throughout their lives tend to maintain better mobility, strength, and overall physical function as they age. This, in turn, contributes to a lower risk of death and a higher quality of life in older age.

4. Is the association between physical activity and mortality explained by genetic selection?

While genetics do play a role in an individual's overall health and longevity, the association between physical activity and reduced mortality is not solely explained by genetic selection. Regular physical activity has beneficial effects on various health markers and disease prevention, which contribute to lower mortality risk. Studies have shown that regardless of genetic predisposition, engaging in physical activity can extend life expectancy and improve health outcomes.

5. What is the association between physical activity and health?

Physical activity is strongly associated with numerous positive health outcomes. It helps maintain a healthy weight, improves cardiovascular health, strengthens muscles and bones, boosts mental health, and reduces the risk of chronic diseases like diabetes, heart disease, and certain cancers. Regular physical activity also contributes to better cognitive function and mental well-being, reducing the risk of depression and anxiety.

6. What is the association between physical activity and mortality among community-dwelling stroke survivors?

Among community-dwelling stroke survivors, engaging in physical activity is associated with reduced mortality risk. Regular physical activity can help improve cardiovascular health, manage blood pressure, enhance mobility, and reduce the risk of recurrent strokes. Stroke survivors who engage in physical activity are more likely to experience improved functional outcomes and have a lower risk of death compared to those who remain inactive.

Related Articles:

Unlock Metabolic Magic: High-Intensity Exercise Boosts Insulin Health

Exercise: Your Lifelong Investment for a Healthier Aging (BLSA Study Reveals)

Meta-analysis Shows Even Small Amounts of Exercise Can Reduce Risk of Death

The Science Behind Vigorous Exercise: Why You Should Prioritize It for Optimal Health

Reference Article

Wang, Y., Nie, J., De Moraes Ferrari, G. L., López, J. P. R., & Rezende, L. F. M. (2021, February 1). Association of Physical Activity Intensity With Mortality. JAMA Internal Medicine. https://doi.org/10.1001/jamainternmed.2020.6331

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